Genetic variability in cisplatin metabolic pathways and outcome of locally advanced head and neck squamous cell carcinoma patients

Advanced head and neck squamous cell carcinoma (HNSCC) patients have been treated with cisplatin (CDDP) chemoradiation, and the variability of treatment effects has been attributed to single nucleotide variants (SNVs) in genes of metabolic pathways. This study investigated the roles of GSTM1, GSTT1,...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana Maria Castro, Altemani, João Maurício Carrasco, Macedo, Ligia Traldi, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556039/
https://www.ncbi.nlm.nih.gov/pubmed/37798436
http://dx.doi.org/10.1038/s41598-023-44040-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556039/
https://www.ncbi.nlm.nih.gov/pubmed/37798436
http://dx.doi.org/10.1038/s41598-023-44040-7

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