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SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies

Amongst the potential contribution of protein or peptide-display systems to study epitopes with relevant immunological features, the RAD display system stands out as a highly stable scaffold protein that allows the presentation of constrained target peptides. Here, we employed the RAD display system...

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Detalles Bibliográficos
Autores principales: Cioffi, Victor Bolsanelli, de Castro-Amarante, Maria Fernanda, Lulla, Aleksei, Andreata-Santos, Robert, Cruz, Mario Costa, Moreno, Ana Carolina Ramos, de Oliveira Silva, Mariângela, de Miranda Peres, Bianca, de Freitas Junior, Lucio Holanda Gondim, Moraes, Carolina Borsoi, Durigon, Edison Luiz, Gordon, Nicola Coker, Hyvönen, Marko, de Souza Ferreira, Luís Carlos, Balan, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556064/
https://www.ncbi.nlm.nih.gov/pubmed/37798298
http://dx.doi.org/10.1038/s41598-023-43720-8