Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis

Pyroptosis is a cell death process that causes inflammation and contributes to numerous diseases. Pyroptosis is mediated by caspase-1 family proteases that cleave the pore-forming protein gasdermin D, causing plasma membrane rupture and release of pathogenic cellular contents. We previously identifi...

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Detalles Bibliográficos
Autores principales: den Hartigh, Andreas B., Loomis, Wendy P., Anderson, Marisa J., Frølund, Bente, Fink, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556065/
https://www.ncbi.nlm.nih.gov/pubmed/37798443
http://dx.doi.org/10.1038/s42003-023-05354-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556065/
https://www.ncbi.nlm.nih.gov/pubmed/37798443
http://dx.doi.org/10.1038/s42003-023-05354-4

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