Cargando…

Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis

Pyroptosis is a cell death process that causes inflammation and contributes to numerous diseases. Pyroptosis is mediated by caspase-1 family proteases that cleave the pore-forming protein gasdermin D, causing plasma membrane rupture and release of pathogenic cellular contents. We previously identifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	den Hartigh, Andreas B., Loomis, Wendy P., Anderson, Marisa J., Frølund, Bente, Fink, Susan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556065/ https://www.ncbi.nlm.nih.gov/pubmed/37798443 http://dx.doi.org/10.1038/s42003-023-05354-4

Ejemplares similares

Diverse small molecules prevent macrophage lysis during pyroptosis
por: Loomis, Wendy P., et al.
Publicado: (2019)

Calcium/P53/Ninjurin 1 Signaling Mediates Plasma Membrane Rupture of Acinar Cells in Severe Acute Pancreatitis
por: Lee, Chehao, et al.
Publicado: (2023)

GABA and Muscimol as Reversible Inactivation Tools in Learning and Memory
por: Majchrzak, M., et al.
Publicado: (2000)

Drosophila Ninjurin A Induces Nonapoptotic Cell Death
por: Broderick, Sarah, et al.
Publicado: (2012)

Ninjurin1 regulates striated muscle growth and differentiation
por: Kny, Melanie, et al.
Publicado: (2019)

Ninjurin2 overexpression promotes glioma cell growth
por: Zhou, Li-Na, et al.
Publicado: (2019)

Elevated plasma Ninjurin-1 levels in atrial fibrillation is associated with atrial remodeling and thromboembolic risk
por: Fang, Chen, et al.
Publicado: (2022)

Ninjurin 1 contributes to TLR-induced inflammation in endothelial cells
por: Jennewein, C, et al.
Publicado: (2012)

Muscimol increases the survival rate and inhibits the inflammatory response in endotoxemic mice
por: Hsu, D-Z, et al.
Publicado: (2009)

Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination
por: Johnson, Sarah A., et al.
Publicado: (2019)

Extrasynaptic δ‐GABA(A) receptors are high‐affinity muscimol receptors
por: Benkherouf, Ali Y., et al.
Publicado: (2019)

AB171. Targeting Ninjurin-1 for future therapy of erectile dysfunction
por: Yin, Guo Nan, et al.
Publicado: (2014)

AB05. Targeting Ninjurin-1 for future therapy of erectile dysfunction
por: Suh, Jun Kyu
Publicado: (2014)

Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk
por: Cheng, Yimin, et al.
Publicado: (2021)

Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts
por: Bae, Sung-Jin, et al.
Publicado: (2019)

Radiation Potentiates Monocyte Infiltration into Tumors by Ninjurin1 Expression in Endothelial Cells
por: Kang, Ju-Hee, et al.
Publicado: (2020)

Pharmacology of Intracisternal or Intrathecal Glycine, Muscimol, and Baclofen in Strychnine-induced Thermal Hyperalgesia of Mice
por: Lee, Il Ok, et al.
Publicado: (2011)

Muscimol-induced inactivation of the ventral prefrontal cortex impairs counting performance in rhesus monkeys
por: Sun, Weiming, et al.
Publicado: (2022)

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
por: de Vasconcelos, Nathalia M., et al.
Publicado: (2018)

Intra-Accumbens Baclofen, But Not Muscimol, Increases Second Order Instrumental Responding for Food Reward in Rats
por: Pulman, Kim G. T., et al.
Publicado: (2012)

Muscimol-induced inactivation of the anterior cingulate cortex does not impair trace fear conditioning in the rat
por: Pezze, Marie A, et al.
Publicado: (2020)

Comparative study between radiofrequency-induced and muscimol-induced inhibition of cultured networks of cortical neuron
por: Lemercier, Clément E., et al.
Publicado: (2022)

Ninjurin 2 overexpression promotes human colorectal cancer cell growth in vitro and in vivo
por: Li, Gang, et al.
Publicado: (2019)

Ninjurin-1: a biomarker for reflecting the process of neuroinflammation after spinal cord injury
por: Weerasinghe-Mudiyanselage, Poornima D. E., et al.
Publicado: (2020)

Phosphorylated MLKL causes plasma membrane rupture
por: Linkermann, Andreas, et al.
Publicado: (2014)

Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus
por: Kim, Eun-Jin, et al.
Publicado: (2021)

Specific oligomerization of the 5-HT1A receptor in the plasma membrane
por: Woehler, Andrew, et al.
Publicado: (2008)

The Oligomeric State of the Plasma Membrane H(+)-ATPase from Kluyveromyces lactis
por: Ruiz-Granados, Yadira G., et al.
Publicado: (2019)

Simultaneous intrathecal injection of muscimol and endomorphin‐1 alleviates neuropathic pain in rat model of spinal cord injury
por: Hosseini, Marjan, et al.
Publicado: (2020)

Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis
por: Poliwoda, Anna, et al.
Publicado: (2020)

Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing
por: Matsuo, Risa, et al.
Publicado: (2022)

Higher-Order Oligomerization Targets Plasma Membrane Proteins and HIV Gag to Exosomes
por: Fang, Yi, et al.
Publicado: (2007)

GABAA agonist muscimol ameliorates learning/memory deficits in streptozocin-induced Alzheimer’s disease non-transgenic rat model
por: Pilipenko, Vladimirs, et al.
Publicado: (2015)

The Effect of Intrathecal Administration of Muscimol on Modulation of Neuropathic Pain Symptoms Resulting from Spinal Cord Injury; an Experimental Study
por: Hosseini, Marjan, et al.
Publicado: (2014)

The GABA(A) receptor agonist muscimol induces an age- and region-dependent form of long-term depression in the mouse striatum
por: Zhang, Xiaoqun, et al.
Publicado: (2016)

Muscimol as a treatment for nerve injury-related neuropathic pain: a systematic review and meta-analysis of preclinical studies
por: Ramawad, Hamzah Adel, et al.
Publicado: (2023)

Pericyte-Specific Ninjurin1 Deletion Attenuates Vessel Maturation and Blood Flow Recovery in Hind Limb Ischemia
por: Minoshima, Akiho, et al.
Publicado: (2018)

miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1
por: Hwang, Su Jung, et al.
Publicado: (2022)

Gamma‐aminobutyric acid(A) receptor agonist, muscimol, increases KiSS‐1 gene expression in hypothalamic cell models
por: Kanasaki, Haruhiko, et al.
Publicado: (2017)

Data on the effect of a muscimol treatment in caspase activation in descending neurons of lampreys after a complete spinal cord injury
por: Sobrido-Cameán, Daniel, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_g0pvi37b4v133fb7ormig50onc