Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia

Acute myeloid leukemia (AML) microenvironment exhibits cellular and molecular differences among various subtypes. Here, we utilize single-cell RNA sequencing (scRNA-seq) to analyze pediatric AML bone marrow (BM) samples from diagnosis (Dx), end of induction (EOI), and relapse timepoints. Analysis of...

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Detalles Bibliográficos
Autores principales: Mumme, Hope, Thomas, Beena E., Bhasin, Swati S., Krishnan, Upaasana, Dwivedi, Bhakti, Perumalla, Pruthvi, Sarkar, Debasree, Ulukaya, Gulay B., Sabnis, Himalee S., Park, Sunita I., DeRyckere, Deborah, Raikar, Sunil S., Pauly, Melinda, Summers, Ryan J., Castellino, Sharon M., Wechsler, Daniel S., Porter, Christopher C., Graham, Douglas K., Bhasin, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556066/
https://www.ncbi.nlm.nih.gov/pubmed/37798266
http://dx.doi.org/10.1038/s41467-023-41994-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556066/
https://www.ncbi.nlm.nih.gov/pubmed/37798266
http://dx.doi.org/10.1038/s41467-023-41994-0

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