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Elucidation of lipid nanoparticle surface structure in mRNA vaccines

Lipid nanoparticles (LNPs) have been used as a carrier for messenger RNA (mRNA) vaccines. Surface properties of LNPs are important to the stability and function of mRNA vaccines. Polyethylene-glycol (PEG) is a functional lipid at the surface of LNPs that improves colloidal stability, increases circu...

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Detalles Bibliográficos
Autores principales: Wang, Mingzhang Maple, Wappelhorst, Caitlin N., Jensen, Erika L., Chi, Ying-Chih Thomas, Rouse, Jason C., Zou, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556076/
https://www.ncbi.nlm.nih.gov/pubmed/37798336
http://dx.doi.org/10.1038/s41598-023-43898-x