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Toll-like receptor 4 promotes the inflammatory response in septic acute kidney injury by promoting p38 mitogen-activated protein kinase phosphorylation

Septic acute kidney injury (AKI) contributes to the mortality and morbidity of sepsis patients. Toll-like Receptor 4 (TLR4) has prominent roles in septic AKI. This study investigated the functions of TLR4 in septic AKI. A septic AKI mouse model was established by cecal ligation and puncture surgery....

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Detalles Bibliográficos
Autores principales: Yue, Linlin, Liu, Xin, Wu, Chaoyu, Lai, Jiying, Wang, Jie, Zhong, Huifeng, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556113/
https://www.ncbi.nlm.nih.gov/pubmed/37605037
http://dx.doi.org/10.1007/s10863-023-09972-9