Tissue‐type plasminogen activator (tPA) homozygous Tyr471His mutation associates with thromboembolic disease

Tissue‐type plasminogen activator (tPA) encoded by PLAT is a major mediator that promotes fibrinolysis and prevents thrombosis. Pathogenetic mutations in PLAT associated with venous thromboembolism have rarely been reported. Here, we report the first case of a homozygous point mutation c.1411T>C...

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Detalles Bibliográficos
Autores principales: Tao, Yanyi, Ma, Jiewen, Feng, Yuanzheng, Gao, Chenggang, Wu, Tingting, Xia, Yunqing, Cheng, Zhipeng, Zhang, Yi, Liu, Tingting, Hu, Yu, Tang, Liang V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556205/
https://www.ncbi.nlm.nih.gov/pubmed/37808270
http://dx.doi.org/10.1002/mco2.392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556205/
https://www.ncbi.nlm.nih.gov/pubmed/37808270
http://dx.doi.org/10.1002/mco2.392

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