Cargando…

Tissue‐type plasminogen activator (tPA) homozygous Tyr471His mutation associates with thromboembolic disease

Tissue‐type plasminogen activator (tPA) encoded by PLAT is a major mediator that promotes fibrinolysis and prevents thrombosis. Pathogenetic mutations in PLAT associated with venous thromboembolism have rarely been reported. Here, we report the first case of a homozygous point mutation c.1411T>C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tao, Yanyi, Ma, Jiewen, Feng, Yuanzheng, Gao, Chenggang, Wu, Tingting, Xia, Yunqing, Cheng, Zhipeng, Zhang, Yi, Liu, Tingting, Hu, Yu, Tang, Liang V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556205/ https://www.ncbi.nlm.nih.gov/pubmed/37808270 http://dx.doi.org/10.1002/mco2.392

Ejemplares similares

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival
por: Chevilley, Arnaud, et al.
Publicado: (2015)

Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA)
por: Lenoir, Sophie, et al.
Publicado: (2019)

The Influence of Tissue Plasminogen Activator I/D Polymorphism on the tPA Response to Exercise
por: COUGHLIN, ADAM M., et al.
Publicado: (2018)

tPA or not tPA? Lysis therapy in the setting of COVID‐19 and ECMO
por: Cromartie, Anjelica, et al.
Publicado: (2022)

Tissue plasminogen activator (tPA) attenuates propofol-induced apoptosis in developing hippocampal neurons
por: Liang, Chao, et al.
Publicado: (2016)

Modulations of the neuronal trafficking of tissue-type plasminogen activator (tPA) influences glutamate release
por: Varangot, Alexandre, et al.
Publicado: (2023)

Alu DNA Polymorphism of Human Tissue Plasminogen Activator (tPA) Gene in Diabetic Jordanian Patients
por: Yasin, Salem R., et al.
Publicado: (2019)

Case Report: Successful Reperfusion of Pulmonary Thromboembolism Using tPA in a Cat
por: Sutton, Blake, et al.
Publicado: (2022)

Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke
por: Chapman, Sherita N, et al.
Publicado: (2014)

Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR
por: Bertrand, T, et al.
Publicado: (2015)

To tPA or Not to tPA: Two Medical-Legal Misadventures of Diagnosing a Cerebrovascular Accident as a Stroke Mimic
por: Moore, Malia J., et al.
Publicado: (2019)

Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate
por: Jeanneret, Valerie, et al.
Publicado: (2016)

Enhanced control of bioactivity of tissue plasminogen activator (tPA) through domain-directed enzymatic oxidation of terminal galactose
por: Mahdi, Wael A., et al.
Publicado: (2022)

A modified mouse model of haemorrhagic transformation associated with tPA administration after thromboembolic stroke
por: Ye, Yang, et al.
Publicado: (2023)

Association of Polymorphisms in Plasminogen Activator Inhibitor-1 (PAI-1), Tissue Plasminogen Activator (tPA), and Renin (REN) with Recurrent Pregnancy Loss in Korean Women
por: Cho, Hee Young, et al.
Publicado: (2021)

Glucocorticoid-Responsive Tissue Plasminogen Activator (tPA) and Its Inhibitor Plasminogen Activator Inhibitor-1 (PAI-1): Relevance in Stress-Related Psychiatric Disorders
por: Mennesson, Marie, et al.
Publicado: (2023)

PSUN171 CORRELATIONS BETWEEN SERUM AND TEAR PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) AND TISSUE PLASMINOGEN ACTIVATOR (tPA) IN PATIENTS WITH DIABETIC RETINOPATHY
por: Jasmiad, Nurbadriah, et al.
Publicado: (2022)

Tissue plasminogen activator (tPA) in the management of predominantly hemorrhagic age-related macular degeneration, milligram/milliliter or microgram/milliliter?
por: Boone, Niels Willem, et al.
Publicado: (2012)

Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators
por: Krstic, Dimitrije, et al.
Publicado: (2012)

Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
por: Marsh, Elisabeth B., et al.
Publicado: (2013)

Kallmann syndrome with a Tyr113His PROKR2 mutation
por: Ha, Jeong-Ha, et al.
Publicado: (2017)

Expression of uPA, tPA, and PAI-1 in Calcified Aortic Valves
por: Kochtebane, Najlah, et al.
Publicado: (2014)

Prognostic value of tissue-type plasminogen activator (tPA) and its complex with the type-1 inhibitor (PAI-1) in breast cancer
por: Witte, J H de, et al.
Publicado: (1999)

PACAP Interacts with PAC(1) Receptors to Induce Tissue Plasminogen Activator (tPA) Expression and Activity in Schwann Cell-Like Cultures
por: Castorina, Alessandro, et al.
Publicado: (2015)

The effect of prehospital notification by emergency medical service on outcomes in patients receiving recombinant tissue-type plasminogen activator (r-tPA)
por: Rafie, Shahram, et al.
Publicado: (2022)

Double-Gene Copromoting Expression Analysis in tPA/GH Transgenic Goat Mammary Epithelial Cells and Thrombolytic Activity of tPA In Vitro
por: Song, Shaozheng, et al.
Publicado: (2022)

Characterization of a Missense Mutation in the Catalytic Domain and a Splicing Mutation of Coagulation Factor X Compound Heterozygous in a Chinese Pedigree
por: Feng, Yuanzheng, et al.
Publicado: (2021)

Low-Dose Slow Infusion Tissue Plasminogen Activator (tPA) in Treatment of Thrombotic Coronary Artery Occlusions: Case Series and Literature Review
por: Akçay, Murat, et al.
Publicado: (2022)

Unintentional intramuscular administration of tPA/DNase for pleural infection
por: Popowicz, Natalia, et al.
Publicado: (2014)

Exosome-Coated tPA/Catalase Nanoformulation for Thrombolytic Therapy
por: Khalil, Sara, et al.
Publicado: (2023)

l-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis
por: Yang, Juan, et al.
Publicado: (2023)

Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke
por: Sun, Yu-Yo, et al.
Publicado: (2014)

Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19
por: Carneiro, Thiago, et al.
Publicado: (2020)

Bronchopleural communication following intrapleural doses of tPA/DNase for empyema
por: Roy, Bapti, et al.
Publicado: (2020)

NF-κB and tPA Signaling in Kidney and Other Diseases
por: White, Samantha, et al.
Publicado: (2020)

Role of Shear Stress and tPA Concentration in the Fibrinolytic Potential of Thrombi
por: Whyte, Claire S., et al.
Publicado: (2021)

721 Defining Bleeding Characteristics in Frostbite Patients Managed with tPA
por: Murphy, Jenna E, et al.
Publicado: (2022)

Von Heyden 471
por: Jennings, A. H. P.
Publicado: (1925)

Effect of the Pleiotropic Drug CNB-001 on Tissue Plasminogen Activator (tPA) Protease Activity in vitro: Support for Combination Therapy to Treat Acute Ischemic Stroke
por: Lapchak, Paul A, et al.
Publicado: (2014)

Plasma Levels of Tissue-Type Plasminogen Activator (tPA) in Normal Aging and Alzheimer's Disease: Links With Cognition, Brain Structure, Brain Function and Amyloid Burden
por: Tomadesso, Clémence, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s3ogh9v83e4qioskiv68ugq02v