Double‐strand DNA break repair: molecular mechanisms and therapeutic targets

Double‐strand break (DSB), a significant DNA damage brought on by ionizing radiation, acts as an initiating signal in tumor radiotherapy, causing cancer cells death. The two primary pathways for DNA DSB repair in mammalian cells are nonhomologous end joining (NHEJ) and homologous recombination (HR),...

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Detalles Bibliográficos
Autores principales: Tan, Jinpeng, Sun, Xingyao, Zhao, Hongling, Guan, Hua, Gao, Shanshan, Zhou, Ping‐Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556206/
https://www.ncbi.nlm.nih.gov/pubmed/37808268
http://dx.doi.org/10.1002/mco2.388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556206/
https://www.ncbi.nlm.nih.gov/pubmed/37808268
http://dx.doi.org/10.1002/mco2.388

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