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Enhanced TrkA signaling impairs basal forebrain-dependent behavior

Basal forebrain cholinergic neurons (BFCNs) modulate cognitive functions such as attention, learning and memory. The NGF/TrkA pathway plays an important role in the development and function of BFCNs, although two mouse models conditionally deleting TrkA expression in the central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Calvo-Enrique, Laura, Lisa, Silvia, Vicente-García, Cristina, Deogracias, Ruben, Arévalo, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556247/
https://www.ncbi.nlm.nih.gov/pubmed/37808473
http://dx.doi.org/10.3389/fnmol.2023.1266983