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Neurodevelopmental disorders and microcephaly: how apoptosis, the cell cycle, tau and amyloid-β precursor protein APPly

Recent studies promote new interest in the intersectionality between autism spectrum disorder (ASD) and Alzheimer’s Disease. We have reported high levels of Amyloid-β Precursor Protein (APP) and secreted APP-alpha (sAPP [Formula: see text] ) and low levels of amyloid-beta (Aβ) peptides 1–40 and 1–42...

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Detalles Bibliográficos
Autores principales: Sokol, Deborah K., Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556256/
https://www.ncbi.nlm.nih.gov/pubmed/37808474
http://dx.doi.org/10.3389/fnmol.2023.1201723