Cargando…
Neurodevelopmental disorders and microcephaly: how apoptosis, the cell cycle, tau and amyloid-β precursor protein APPly
Recent studies promote new interest in the intersectionality between autism spectrum disorder (ASD) and Alzheimer’s Disease. We have reported high levels of Amyloid-β Precursor Protein (APP) and secreted APP-alpha (sAPP [Formula: see text] ) and low levels of amyloid-beta (Aβ) peptides 1–40 and 1–42...
Autores principales: | Sokol, Deborah K., Lahiri, Debomoy K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556256/ https://www.ncbi.nlm.nih.gov/pubmed/37808474 http://dx.doi.org/10.3389/fnmol.2023.1201723 |
Ejemplares similares
-
APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
por: Sokol, Deborah K., et al.
Publicado: (2023) -
Novel Contribution of Secreted Amyloid-β Precursor Protein to White Matter Brain Enlargement in Autism Spectrum Disorder
por: Sokol, Deborah K., et al.
Publicado: (2019) -
Novel Roles of Amyloid-Beta Protein Precursor Metabolites in Fragile X Syndrome and Autism
por: Westmark, Cara J., et al.
Publicado: (2016) -
Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker
por: Ray, Balmiki, et al.
Publicado: (2011) -
Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway
por: Lahiri, Debomoy K., et al.
Publicado: (2013)