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RAD51 as a biomarker for homologous recombination deficiency in high‐grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test

The RAD51 test is emerging as a promising biomarker for the assessment of functional homologous recombination deficiency (HRD). Yet, the robustness and reproducibility of the immunofluorescence‐based RAD51 test, in different academic laboratories, have not been systematically investigated. Therefore...

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Detalles Bibliográficos
Autores principales: Kramer, Claire JH, Llop‐Guevara, Alba, Yaniz‐Galende, Elisa, Pellegrino, Benedetta, ter Haar, Natalja T, Herencia‐Ropero, Andrea, Campanini, Nicoletta, Musolino, Antonino, Bosse, Tjalling, Leary, Alexandra, Serra, Violeta, Vreeswijk, Maaike PG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556259/
https://www.ncbi.nlm.nih.gov/pubmed/37504067
http://dx.doi.org/10.1002/cjp2.336