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Endocortical Trabecularization in Acromegaly: The Cause for the Paradoxically Increased Vertebral Fracture Risk?

Growth hormone (GH) is nonphysiologically increased in acromegaly, stimulating target tissues directly and indirectly via insulin‐like growth factor type 1 (IGF‐1). Despite GH having anabolic effects on bone growth and renewal, the risk of vertebral fractures is paradoxically increased in acromegaly...

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Detalles Bibliográficos
Autores principales: Heck, Ansgar, Godang, Kristin, Lekva, Tove, Markussen, Kjersti Norman, De Vincentis, Sara, Ueland, Thor, Bollerslev, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556260/
https://www.ncbi.nlm.nih.gov/pubmed/37808394
http://dx.doi.org/10.1002/jbm4.10787