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Single‐Cell Integration of BMD GWAS Results Prioritize Candidate Genes Influencing Age‐Related Bone Loss

The regulation of bone mineral density (BMD) is highly influenced by genetics and age. Although genome‐wide association studies (GWAS) for BMD have uncovered many genes through their proximity to associated variants (variant nearest‐neighbor [VNN] genes), the cell‐specific mechanisms of each VNN gen...

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Detalles Bibliográficos
Autores principales: Doolittle, Madison L., Khosla, Sundeep, Saul, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556272/
https://www.ncbi.nlm.nih.gov/pubmed/37808401
http://dx.doi.org/10.1002/jbm4.10795