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DAT (deacylating autotransporter toxin) from Bordetella parapertussis demyristoylates Gα(i) GTPases and contributes to cough
The pathogenic bacteria Bordetella pertussis and Bordetella parapertussis cause pertussis (whooping cough) and pertussis-like disease, respectively, both of which are characterized by paroxysmal coughing. We previously reported that pertussis toxin (PTx), which inactivates heterotrimeric GTPases of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556565/ https://www.ncbi.nlm.nih.gov/pubmed/37748060 http://dx.doi.org/10.1073/pnas.2308260120 |