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DAT (deacylating autotransporter toxin) from Bordetella parapertussis demyristoylates Gα(i) GTPases and contributes to cough

The pathogenic bacteria Bordetella pertussis and Bordetella parapertussis cause pertussis (whooping cough) and pertussis-like disease, respectively, both of which are characterized by paroxysmal coughing. We previously reported that pertussis toxin (PTx), which inactivates heterotrimeric GTPases of...

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Detalles Bibliográficos
Autores principales:	Hiramatsu, Yukihiro, Nishida, Takashi, Ota, Natsuko, Tamaki, Yuki, Nugraha, Dendi K., Horiguchi, Yasuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556565/ https://www.ncbi.nlm.nih.gov/pubmed/37748060 http://dx.doi.org/10.1073/pnas.2308260120

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