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Methylmercury (MeHg) transcriptionally regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) in Hepa-1c1c7 cells
The detoxification of quinones through NAD(P)H:quinone oxidoreductase (NQO1) is a crucial mechanism to maintain cellular homeostasis. The exposure to heavy metals, specifically methylmercury (MeHg), induces several antioxidant enzymes, including NQO1. The nuclear factor erythroid 2-related factor-2...
Autores principales: | Alqahtani, Mohammed A., El-Ghiaty, Mahmoud A., El-Mahrouk, Sara R., El-Kadi, Ayman O.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556580/ https://www.ncbi.nlm.nih.gov/pubmed/37808441 http://dx.doi.org/10.1016/j.crtox.2023.100126 |
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