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Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation

The phenomenon of protein phase separation (PPS) underlies a wide range of cellular functions. Correspondingly, the dysregulation of the PPS process has been associated with numerous human diseases. To enable therapeutic interventions based on the regulation of this association, possible targets sho...

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Detalles Bibliográficos
Autores principales: Lim, Christine M., González Díaz, Alicia, Fuxreiter, Monika, Pun, Frank W., Zhavoronkov, Alex, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556643/
https://www.ncbi.nlm.nih.gov/pubmed/37774095
http://dx.doi.org/10.1073/pnas.2300215120