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Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis

INTRODUCTION: Previous work in humans has demonstrated that both innate and adaptive immune signaling pathways contribute to the pathogenesis of idiopathic inflammatory myopathy (IIM), a systemic autoimmune disease targeting muscle as well as extra-muscular organs. To better define interactive signa...

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Detalles Bibliográficos
Autores principales: Reay, Daniel P., Tabib, Tracy, Wang, Ying, Oriss, Timothy B., Young, Nicholas A., Lafyatis, Robert A., Jarjour, Wael N., Clemens, Paula R., Ascherman, Dana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556668/
https://www.ncbi.nlm.nih.gov/pubmed/37809058
http://dx.doi.org/10.3389/fimmu.2023.1238221