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Succinate metabolism: a promising therapeutic target for inflammation, ischemia/reperfusion injury and cancer
Succinate serves as an essential circulating metabolite within the tricarboxylic acid (TCA) cycle and functions as a substrate for succinate dehydrogenase (SDH), thereby contributing to energy production in fundamental mitochondrial metabolic pathways. Aberrant changes in succinate concentrations ha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556696/ https://www.ncbi.nlm.nih.gov/pubmed/37808079 http://dx.doi.org/10.3389/fcell.2023.1266973 |