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Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection

Chronic inflammation is recognized as a major risk factor for the severity of HIV infection. Whether metabolism reprogramming of macrophages caused by HIV-1 is related to chronic inflammatory activation, especially M1 polarization of macrophages, is inconclusive. Here, we show that HIV-1 infection i...

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Detalles Bibliográficos
Autores principales: Zhang, Junhan, Yuan, Zongxiang, Li, Xuanrong, Wang, Fengyi, Wei, Xueqin, Kang, Yiwen, Mo, Chuye, Jiang, Junjun, Liang, Hao, Ye, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
https://www.ncbi.nlm.nih.gov/pubmed/37798121
http://dx.doi.org/10.26508/lsa.202302148