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Acute protein kinase C beta inhibition preserves coronary endothelial function after cardioplegic hypoxia/reoxygenation

OBJECTIVE: Protein kinase C (PKC) influences myocardial contractility and susceptibility to long-term cardiac dysfunction after ischemia–reperfusion injury. In diabetes, PKC inhibition has a protective effect in terms of microvascular dysfunction. SK-channel dysfunction also influences endothelial d...

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Detalles Bibliográficos
Autores principales: Kant, Shawn, Xing, Hang, Liu, Yuhong, Harrington, Elizabeth O., Sellke, Frank W., Feng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556935/
https://www.ncbi.nlm.nih.gov/pubmed/37808045
http://dx.doi.org/10.1016/j.xjon.2023.06.014