Anastomotic stenosis of bioengineered trachea grafts is driven by transforming growth factor β1-induced signaling, proinflammatory macrophages, and delayed epithelialization

OBJECTIVE: Anastomotic stenosis caused by hypertrophic granulation tissue often develops in response to orthotopically implanted bioengineered tracheal grafts. To determine mechanisms responsible for the development and persistence of this granulation tissue, we looked for changes in gene expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Weber, Joanna, Martins, Russell Seth, Muslim, Zaid, Baig, Mirza Zain, Poulikidis, Kostantinos, Al Shetawi, Al Haitham, Bhora, Faiz Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Thoracic: Trachea: Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556948/
https://www.ncbi.nlm.nih.gov/pubmed/37808012
http://dx.doi.org/10.1016/j.xjon.2023.07.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556948/
https://www.ncbi.nlm.nih.gov/pubmed/37808012
http://dx.doi.org/10.1016/j.xjon.2023.07.016

Ejemplares similares