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Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients

Our cellular genome is susceptible to cytotoxic lesions which include single strand breaks and double strand breaks among other lesions. Ataxia telangiectasia mutated (ATM) protein was one of the first DNA damage sensor proteins to be discovered as being involved in DNA repair and as well as in telo...

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Detalles Bibliográficos
Autores principales: Srikanth, Prarthana, Chowdhury, Amit Roy, Low, Grace Kah Mun, Saraswathy, Radha, Fujimori, Akira, Banerjee, Birendranath, Martinez-Lopez, Wilner, Hande, M. Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ScienceOpen 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557037/
https://www.ncbi.nlm.nih.gov/pubmed/38021281
http://dx.doi.org/10.14293/genint.13.1.003