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Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients
Our cellular genome is susceptible to cytotoxic lesions which include single strand breaks and double strand breaks among other lesions. Ataxia telangiectasia mutated (ATM) protein was one of the first DNA damage sensor proteins to be discovered as being involved in DNA repair and as well as in telo...
Autores principales: | Srikanth, Prarthana, Chowdhury, Amit Roy, Low, Grace Kah Mun, Saraswathy, Radha, Fujimori, Akira, Banerjee, Birendranath, Martinez-Lopez, Wilner, Hande, M. Prakash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ScienceOpen
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557037/ https://www.ncbi.nlm.nih.gov/pubmed/38021281 http://dx.doi.org/10.14293/genint.13.1.003 |
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