Concise and Scalable Radiosynthesis of (+)-[(18)F]MDL100907 as a Serotonin 5-HT(2A) Receptor Antagonist for PET

[Image: see text] 5-Hydroxytryptamine (5-HT(2A)) receptors play an important role in several psychiatric disorders. In order to investigate the serotonin (5-HT) receptor in vivo, reliable syntheses are required for positron emission tomography (PET) 5-HT radioligands. Owing to the excellent in vivo...

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Detalles Bibliográficos
Autores principales: Chavan, Lahu N., Voll, Ronald, Sanchez, Mar M., Nye, Jonathon A., Goodman, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557077/
https://www.ncbi.nlm.nih.gov/pubmed/37748194
http://dx.doi.org/10.1021/acschemneuro.3c00382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557077/
https://www.ncbi.nlm.nih.gov/pubmed/37748194
http://dx.doi.org/10.1021/acschemneuro.3c00382

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