Helicase Activity Modulation with On-Demand Light-Based Conformational Control

[Image: see text] Engineering a protein variant with a desired role relies on deep knowledge of the relationship between a protein's native structure and function. Using our structural understanding of a regulatory subdomain found in a family of DNA helicases, we engineered novel helicases for...

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Detalles Bibliográficos
Autores principales: Bobrovnikov, Dmitriy, Makurath, Monika A., Wolfe, Clara H., Chemla, Yann R., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557133/
https://www.ncbi.nlm.nih.gov/pubmed/37739407
http://dx.doi.org/10.1021/jacs.3c05254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557133/
https://www.ncbi.nlm.nih.gov/pubmed/37739407
http://dx.doi.org/10.1021/jacs.3c05254

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