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Helicase Activity Modulation with On-Demand Light-Based Conformational Control
[Image: see text] Engineering a protein variant with a desired role relies on deep knowledge of the relationship between a protein's native structure and function. Using our structural understanding of a regulatory subdomain found in a family of DNA helicases, we engineered novel helicases for...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557133/ https://www.ncbi.nlm.nih.gov/pubmed/37739407 http://dx.doi.org/10.1021/jacs.3c05254 |