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Immunocomplexed Antigen Capture and Identification by Native Top-Down Mass Spectrometry

[Image: see text] Antibody–antigen interactions are central to the immune response. Variation of protein antigens such as isoforms and post-translational modifications can alter their antibody binding sites. To directly connect the recognition of protein antigens with their molecular composition, we...

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Detalles Bibliográficos
Autores principales: McGee, John P., Melani, Rafael D., Des Soye, Ben, Croote, Derek, Winton, Valerie, Quake, Stephen R., Kafader, Jared O., Kelleher, Neil L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557138/
https://www.ncbi.nlm.nih.gov/pubmed/37683262
http://dx.doi.org/10.1021/jasms.3c00235