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TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage

BACKGROUND: Cisplatin is a widely used and effective chemotherapeutic agent against cancer. However, nephrotoxicity is one of the most common side effects of cisplatin, and it can proceed to acute kidney injury (AKI). Studies have reported that activation of transient receptor potential ankyrin-1 (T...

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Detalles Bibliográficos
Autores principales: Deng, Fei, Zhang, Heping, Zhou, Wei, Ma, Shijie, Kang, Yuwei, Yang, Wei, Zhao, Liangbin, Qin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557178/
https://www.ncbi.nlm.nih.gov/pubmed/37798747
http://dx.doi.org/10.1186/s12967-023-04351-9