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IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells

BACKGROUND: Antigenic stimulation through cross-linking the IgE receptor and epithelial cell-derived cytokine IL-33 are potent stimuli of mast cell (MC) activation. Moreover, IL-33 primes a variety of cell types, including MCs to respond more vigorously to external stimuli. However, target genes ind...

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Detalles Bibliográficos
Autores principales: Gao, Junfeng, Li, Yapeng, Guan, Xiaoyu, Mohammed, Zahraa, Gomez, Gregorio, Hui, Yvonne, Zhao, Dianzheng, Oskeritzian, Carole A., Huang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557204/
https://www.ncbi.nlm.nih.gov/pubmed/37798647
http://dx.doi.org/10.1186/s12864-023-09702-w