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Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice

BACKGROUND: Some patients show persistent cognitive decline for weeks, months or even years after surgery, which seriously affects their long-term prognosis and quality of life. However, most previous basic studies have focused mainly on the mechanisms of early postoperative cognitive decline, where...

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Detalles Bibliográficos
Autores principales: Li, Xiaowei, Wang, Hong, Zhang, Qidi, Sun, Xiaobin, Zhang, Mengyuan, Wang, Gongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557222/
https://www.ncbi.nlm.nih.gov/pubmed/37798730
http://dx.doi.org/10.1186/s12974-023-02910-x