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A circulating cell-free DNA methylation signature for the detection of hepatocellular carcinoma

To address the shortcomings of current hepatocellular carcinoma (HCC) surveillance tests, we set out to find HCC-specific methylation markers and develop a highly sensitive polymerase chain reaction (PCR)-based method to detect them in circulating cell-free DNA (cfDNA). The analysis of large methylo...

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Detalles Bibliográficos
Autores principales: Kim, Si-Cho, Kim, Da-Won, Cho, Eun Ju, Lee, Jin-Young, Kim, Jiwon, Kwon, Chaesun, Kim-Ha, Jeongsil, Hong, Suk Kyun, Choi, YoungRok, Yi, Nam-Joon, Lee, Kwang-Woong, Suh, Kyung-Suk, Kim, Won, Kim, Woojin, Kim, Hyunsoo, Kim, Yoon Jun, Yoon, Jung-Hwan, Yu, Su Jong, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557228/
https://www.ncbi.nlm.nih.gov/pubmed/37803338
http://dx.doi.org/10.1186/s12943-023-01872-1