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Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis

BACKGROUND: Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs) have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of extracellular vesicles from placenta-derived MSCs (Pd-MSCs-EVs) on liver fibrosis at 3D/2D levels and explore the potent...

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Detalles Bibliográficos
Autores principales: Zheng, Wenjie, Bian, Saiyan, Qiu, Shi, Bishop, Colin E., Wan, Meimei, Xu, Nuo, Sun, Xieyin, Sequeira, Russel Clive, Atala, Anthony, Gu, Zhifeng, Zhao, Weixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557276/
https://www.ncbi.nlm.nih.gov/pubmed/37798761
http://dx.doi.org/10.1186/s41232-023-00297-z