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Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis
BACKGROUND: Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs) have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of extracellular vesicles from placenta-derived MSCs (Pd-MSCs-EVs) on liver fibrosis at 3D/2D levels and explore the potent...
Autores principales: | Zheng, Wenjie, Bian, Saiyan, Qiu, Shi, Bishop, Colin E., Wan, Meimei, Xu, Nuo, Sun, Xieyin, Sequeira, Russel Clive, Atala, Anthony, Gu, Zhifeng, Zhao, Weixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557276/ https://www.ncbi.nlm.nih.gov/pubmed/37798761 http://dx.doi.org/10.1186/s41232-023-00297-z |
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