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Phase III clinical trial of autologous CD34 + cell transplantation to accelerate fracture nonunion repair

BACKGROUND: We previously demonstrated that CD34 + cell transplantation in animals healed intractable fractures via osteogenesis and vasculogenesis; we also demonstrated the safety and efficacy of this cell therapy in an earlier phase I/II clinical trial conducted on seven patients with fracture non...

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Detalles Bibliográficos
Autores principales: Kuroda, Ryosuke, Niikura, Takahiro, Matsumoto, Tomoyuki, Fukui, Tomoaki, Oe, Keisuke, Mifune, Yutaka, Minami, Hironobu, Matsuoka, Hiroshi, Yakushijin, Kimikazu, Miyata, Yoshiharu, Kawamoto, Shinichiro, Kagimura, Tatsuo, Fujita, Yasuyuki, Kawamoto, Atsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557317/
https://www.ncbi.nlm.nih.gov/pubmed/37798633
http://dx.doi.org/10.1186/s12916-023-03088-y