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Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies

RNA binding proteins (RBPs) are key regulators of RNA processing and cellular function. Technologies to discover RNA targets of RBPs such as TRIBE (targets of RNA binding proteins identified by editing) and STAMP (surveying targets by APOBEC1 mediated profiling) utilize fusions of RNA base-editors (...

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Detalles Bibliográficos
Autores principales: Medina-Munoz, Hugo C., Kofman, Eric, Jagannatha, Pratibha, Boyle, Evan A., Yu, Tao, Jones, Krysten L., Mueller, Jasmine R., Lykins, Grace D., Doudna, Andrew T., Park, Samuel S., Blue, Steven M., Ranzau, Brodie L., Kohli, Rahul M., Komor, Alexis C., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557582/
https://www.ncbi.nlm.nih.gov/pubmed/37808757
http://dx.doi.org/10.1101/2023.09.25.558915