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Ancient genomic linkage couples metabolism with erythroid development

Generation of mature cells from progenitors requires tight coupling of differentiation and metabolism. During erythropoiesis, erythroblasts are required to massively upregulate globin synthesis then clear extraneous material and enucleate to produce erythrocytes(1–3). Nprl3 has remained in synteny w...

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Detalles Bibliográficos
Autores principales: Preston, Alexandra E., Frost, Joe N., Badat, Mohsin, Teh, Megan, Armitage, Andrew E., Norfo, Ruggiero, Wideman, Sarah K., Hanifi, Muhammad, White, Natasha, Roy, Noémi, Ghesquiere, Bart, Babbs, Christian, Kassouf, Mira, Davies, James, Hughes, Jim R., Beagrie, Rob, Higgs, Douglas R., Drakesmith, Hal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557585/
https://www.ncbi.nlm.nih.gov/pubmed/37808769
http://dx.doi.org/10.1101/2023.09.25.558944