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Ancient genomic linkage couples metabolism with erythroid development
Generation of mature cells from progenitors requires tight coupling of differentiation and metabolism. During erythropoiesis, erythroblasts are required to massively upregulate globin synthesis then clear extraneous material and enucleate to produce erythrocytes(1–3). Nprl3 has remained in synteny w...
Autores principales: | Preston, Alexandra E., Frost, Joe N., Badat, Mohsin, Teh, Megan, Armitage, Andrew E., Norfo, Ruggiero, Wideman, Sarah K., Hanifi, Muhammad, White, Natasha, Roy, Noémi, Ghesquiere, Bart, Babbs, Christian, Kassouf, Mira, Davies, James, Hughes, Jim R., Beagrie, Rob, Higgs, Douglas R., Drakesmith, Hal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557585/ https://www.ncbi.nlm.nih.gov/pubmed/37808769 http://dx.doi.org/10.1101/2023.09.25.558944 |
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