Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates

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Nucleoli are surrounded by Pericentromeric Heterochromatin (PCH), reflecting a close spatial association between the two largest biomolecular condensates in eukaryotic nuclei. This nuclear organizational feature is highly conserved and is disrupted in diseased states like senescence, however, the me...

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Detalles Bibliográficos
Autores principales: Rajshekar, Srivarsha, Adame-Arana, Omar, Bajpai, Gaurav, Lin, Kyle, Colmenares, Serafin, Safran, Samuel, Karpen, Gary H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557603/
https://www.ncbi.nlm.nih.gov/pubmed/37808710
http://dx.doi.org/10.1101/2023.07.06.547894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557603/
https://www.ncbi.nlm.nih.gov/pubmed/37808710
http://dx.doi.org/10.1101/2023.07.06.547894

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