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Improved CAR-T cell activity associated with increased mitochondrial function primed by galactose

CD19 CAR-T cells have led to durable remissions in patients with refractory B-cell malignancies; nevertheless, most patients eventually relapse in the long term. Many interventions aimed at improving current products have been reported, with a subset of them focusing on a direct or indirect link to...

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Detalles Bibliográficos
Autores principales: Gross, Golda, Alkadieri, Suha, Meir, Amilia, Itzhaki, Orit, Aharony-Tevet, Yarden, Yosef, Shahar Ben, Zenab, Angi, Shbiro, Liat, Toren, Amos, Yardeni, Tal, Jacoby, Elad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557609/
https://www.ncbi.nlm.nih.gov/pubmed/37808778
http://dx.doi.org/10.1101/2023.09.23.559091