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Suppression of HIV and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters

HIV-associated neurological disorder (HAND) is a serious complication of HIV infection, marked by neurotoxicity induced by viral proteins like Tat. Substance abuse exacerbates neurocognitive impairment in people living with HIV. There is an urgent need for effective therapeutic strategies to combat...

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Detalles Bibliográficos
Autores principales: Cui, B. Celia, Aksenova, Marina, Sikirzhytskaya, Aliaksandra, Odhiambo, Diana, Korunova, Elizaveta, Sikirzhytski, Vitali, Ji, Hao, Altomare, Diego, Broude, Eugenia, Frizzell, Norma, Booze, Rosemarie, Wyatt, Michael D., Shtutman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557618/
https://www.ncbi.nlm.nih.gov/pubmed/37808776
http://dx.doi.org/10.1101/2023.09.25.559154