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SETD2 maintains nuclear lamina stability to safeguard the genome

Histone methyltransferases play essential roles in the organization and function of chromatin. They are also frequently mutated in human diseases including cancer(1). One such often mutated methyltransferase, SETD2, associates co-transcriptionally with RNA polymerase II and catalyzes histone H3 lysi...

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Detalles Bibliográficos
Autores principales: Khan, Abid, Metts, James M., Collins, Lucas C., Mills, C. Allie, Li, Kelin, Brademeyer, Amanda L., Bowman, Brittany M., Major, M. Ben, Aubé, Jeffrey, Herring, Laura E., Davis, Ian J., Strahl, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557632/
https://www.ncbi.nlm.nih.gov/pubmed/37808753
http://dx.doi.org/10.1101/2023.09.28.560032