Multimodal identification of rare potent effector CD8 T cells in solid tumors

Antitumor immunity is driven by CD8 T cells, yet we lack signatures for the exceptional effectors in tumors, amongst the vast majority of CD8 T cells undergoing exhaustion. By leveraging the measurement of a canonical T cell activation protein (CD69) together with its RNA (Cd69), we found a larger c...

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Detalles Bibliográficos
Autores principales: Ray, Arja, Bassette, Molly, Hu, Kenneth H., Pass, Lomax F., Samad, Bushra, Combes, Alexis, Johri, Vrinda, Davidson, Brittany, Hernandez, Grace, Zaleta-Linares, Itzia, Krummel, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557647/
https://www.ncbi.nlm.nih.gov/pubmed/37808790
http://dx.doi.org/10.1101/2023.09.26.559470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557647/
https://www.ncbi.nlm.nih.gov/pubmed/37808790
http://dx.doi.org/10.1101/2023.09.26.559470

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