Nucleotide Excision Repair of Aflatoxin-induced DNA Damage within the 3D Human Genome Organization

Aflatoxin B1 (AFB1), a potent mycotoxin, is one of the two primary risk factors that cause liver cancer. In the liver, the bioactivated AFB1 intercalates into the DNA double helix to form a bulky DNA adduct which will lead to mutation if left unrepaired. We have adapted the tXR-seq method to measure...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yiran, Adeel, Muhammad Muzammal, Sancar, Aziz, Li, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557652/
https://www.ncbi.nlm.nih.gov/pubmed/37808841
http://dx.doi.org/10.1101/2023.09.27.559858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557652/
https://www.ncbi.nlm.nih.gov/pubmed/37808841
http://dx.doi.org/10.1101/2023.09.27.559858

Ejemplares similares