Cargando…
Nucleotide Excision Repair of Aflatoxin-induced DNA Damage within the 3D Human Genome Organization
Aflatoxin B1 (AFB1), a potent mycotoxin, is one of the two primary risk factors that cause liver cancer. In the liver, the bioactivated AFB1 intercalates into the DNA double helix to form a bulky DNA adduct which will lead to mutation if left unrepaired. We have adapted the tXR-seq method to measure...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557652/ https://www.ncbi.nlm.nih.gov/pubmed/37808841 http://dx.doi.org/10.1101/2023.09.27.559858 |