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A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia

Retinal degeneration in mammals causes permanent loss of vision, due to an inability to regenerate naturally. Some non-mammalian vertebrates show robust regeneration, via Muller glia (MG). We have recently made significant progress in stimulating adult mouse MG to regenerate functional neurons by tr...

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Detalles Bibliográficos
Autores principales: Tresenrider, Amy, Hooper, Marcus, Todd, Levi, Kierney, Faith, Blasdel, Nicolai, Trapnell, Cole, Reh, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557658/
https://www.ncbi.nlm.nih.gov/pubmed/37808650
http://dx.doi.org/10.1101/2023.09.26.559569