An enhancer RNA recruits MLL1 to regulate transcription of Myb

The Myb proto-oncogene encodes the transcription factor c-MYB, which is critical for hematopoiesis. Distant enhancers of Myb form a hub of interactions with the Myb promoter. We identified a long non-coding RNA (Myrlin) originating from the −81 kb murine Myb enhancer. Myrlin and Myb are coordinately...

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Detalles Bibliográficos
Autores principales: Kim, Juhyun, Diaz, Luis F., Miller, Matthew J., Leadem, Benjamin, Krivega, Ivan, Dean, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557664/
https://www.ncbi.nlm.nih.gov/pubmed/37808852
http://dx.doi.org/10.1101/2023.09.26.559528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557664/
https://www.ncbi.nlm.nih.gov/pubmed/37808852
http://dx.doi.org/10.1101/2023.09.26.559528

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